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The alveolar immune cell landscape is dysregulated in checkpoint inhibitor pneumonitis

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Figure

Figure 1. Radiographic presentation of CIP. Rep-resentative computed tomography images of an
Figure 3. BAL lymphocytosis in patients with CIP. Scatter plots showing number of ((A) CD4+B) CD8+, (C) CD14+, and (D) CD16+ T cells (A and B) and monocytes (C and D), respectively, in control and CIP samples
Figure 4. T cell populations in CIP. Unsupervised clustering of T cells in BALF samples of patients without (control, n = 6) and with CIP (n = 12)
Figure 5. Abnormal T cell subsets in CIP. Differential cluster map (center) shows clusters where the number of cells within the cluster were increased by 95% in CIP and controls, scatter plot showing PD-1/CTLA-4 MFI in selected clusters; (iv) a CD3CD4/TNF-
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