• No results found

Targeting the epigenetic readers in Ewing Sarcoma inhibits the oncogenic transcription factor EWS/Fli1

N/A
N/A
Protected

Academic year: 2020

Share "Targeting the epigenetic readers in Ewing Sarcoma inhibits the oncogenic transcription factor EWS/Fli1"

Copied!
16
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Figure 1: ewing sarcoma cell lines overexpress brd2, brd3, brd4 and eWs-Fli1 at mrnAs level and are sensitive to bet proteins inhibition
Figure 2: JQ1 inhibits the clonogenicity, the migratory potential and induces both a G1-phase cell cycle arrest and the apoptosis of human ewing sarcoma cell lines
Figure 3: JQ1(+) treatment in ewing sarcoma cells induces a dose- and a time-dependent eWs-Fli1 down-regulation
Figure 4: JQ1(+) treatment in ewing sarcoma cells induces a dose- and a time-dependent modulation of pathways under the control of eWs-Fli1
+2

References

Related documents

Finger Paint is not a complex application to develop, but serves as a basis for developing and testing the cross-platform abstract interface to ARToolKit, and uses all the

This essay asserts that to effectively degrade and ultimately destroy the Islamic State of Iraq and Syria (ISIS), and to topple the Bashar al-Assad’s regime, the international

19% serve a county. Fourteen per cent of the centers provide service for adjoining states in addition to the states in which they are located; usually these adjoining states have

Field experiments were conducted at Ebonyi State University Research Farm during 2009 and 2010 farming seasons to evaluate the effect of intercropping maize with

For comparison between diffusion metrics at baseline and af- ter neurosurgical intervention, short-term follow-up (with- in 3 months since surgical intervention), and long-term

The NTSB report stated that the high velocity of the diesel in the tank fill piping and the turbulence created in the sump area resulted in the generation of increase static charge

Results suggest that the probability of under-educated employment is higher among low skilled recent migrants and that the over-education risk is higher among high skilled

innovation in payment systems, in particular the infrastructure used to operate payment systems, in the interests of service-users 3.. to ensure that payment systems