• No results found

Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma

N/A
N/A
Protected

Academic year: 2020

Share "Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma"

Copied!
17
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Figure 1: A stepwise increase of Orai1 in oral/oropharyngeal carcinogenesis. A.normal human oral keratinocyte (NHOK), 3 precancerous, non-tumorigenic immortalized oral epithelial cell lines (NOK-SI, OKF6/tert, and HOK-16B) and 10 OSCC cell lines (HOK-16B-B
Figure 2: the dominant negative Orai1 mutant (E106Q) suppresses tumorigenicity of Oscc in vivodetermined by xenograft tumor assay
Figure 3: the dominant negative Orai1 mutant (E106Q) inhibits csc phenotype. A. Effect of E106Q on self-renewal capacity of two OSCC cell lines, SCC4 and HOK-16B BapT, was determined by tumor sphere formation assay
Figure 4: Orai1 expression is enriched in csc populations of Oscc. A.was determined in ALDH1 Expressions of Orai1, stemness transcription factors (Nanog, Oct4, KLF4, Lin28A, and Sox2) and ALDH1were assessed in tumor spheres (CSC-enriched population) and co
+4

References

Related documents

using 16 cameras surrounding a human (we can change the number of cameras). The human makes several gestures and the system memorizes each gesture as an individual VAMBAM. In

The aim of the present study was to gain a racquet sports coaches ’ perspective on the importance of anthropometry, physical performance measures, and motor coordination in

In hovering flight (there is no climbing or forward speed), the engines have to provide enough thrust to compensate the aircraft’s weight, so the thrust per engine is the

Bagian-bagian dari mangrove yang digunakan untuk obat tradisional yaitu: daun, getah, buah dan seluruh bagian tanaman. Bentuk pemanfaatan dari mangrove di Semenan- jung

The main independent variables included refugees’ race, prior victimization, prior police contact, fear of crime, and poor communication (see Table 1).. Race was a

activities only when they are focused and active in learning activities. The next section summarizes the students' responses to the learning modules provided in the

For anionic surfactants added p-BQ solution, fluorescence intensity initially decreased and then increased at their higher concentration with a red shift of 25nm with