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SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate

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Academic year: 2020

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Figure

Figure 1: (A) Macroscopical appearance of tumors from xenografted TCam-2, 2102EP and TCam-2-∆SOX2 clones
Figure 2: (A, B) Expression microarray (A) and qRT-PCR (B) data of indicated genes related to the in vivo reprogramming, pluripotency, seminoma-ness, signaling pathways and epigentics
Figure 3: IHC staining of indicated proteins in TCam-2-∆SOX2 clones. Tumor tissues from xenografted 2102EP cells were stained as control
Figure 4: ChIP followed by qPCR-analysis of SOX2-enrichment at the SOX2 binding sites within indicated genes
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