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Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells

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Figure

Figure 1: Expression and knockdown effects of TOPK and MELK in kidney cancer cell lines
Figure 2: Both TOPK and MELK regulate expression of FOXM1. A. Silencing of TOPK expression downregulated FOXM1 protein level as similar as MELK affected on it in kidney cancer cell lines
Figure 3: FOXM1 also regulates TOPK and MELK expression. Expression level of TOPK and MELK were examined by RT-PCR after depletion or overexpression of FOXM1 in kidney cancer cells
Figure 4: In vitro anti-proliferative effects of OTS514 and OTS167 in kidney cancer cell lines
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