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Nuclear factor one B ( NFIB ) encodes a subtype-specific tumour suppressor in glioblastoma

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Figure 1: NFIB expression correlates inversely with astrocytoma grade. (A) NFIB expression is higher in WHO grade II and III astrocytic gliomas (II/III) and lower in GBM
Figure 2: NFIB expression and copy number correlate with glioma patient survival. (A) GBM patients with higher NFIBexpression survive significantly longer than those with lower NFIB expression
Figure 3: Ectopic expression of NFIB in human classical and mesenchymal GBM inhibits tumour growth
Figure 4: Ectopic expression of NFIB in human mesenchymal GBM induces differentiation, inhibits proliferation and inhibits self-renewal
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