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Novel Cell Cycle Regulation in Breast Cancer Treatment Resistance

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Figure

Figure 1. Schematic representation of estrogen receptor domains. The estrogen receptorstructure contains domains A-F
Figure 2. Schematic diagram of estrogen receptor signalling. (A) Classical activation ofsignalling, where after dimerization, transcription factors such as Fos and Jun tether theE2-ER dimers to specific promoters to initiate transcription
Figure 3. Schematic of Speedy/RINGO domain organization and Speedy/RINGOisoforms. (A) A schematic of Speedy/RINGO protein domains
Figure 4. Spy1 is upregulated upon activation of the estrogen receptor. (A) MCF7 cellsERK1/2 inhibitor, followed by SDS-PAGE and IB
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