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<p>Transcription factor <em>Nrf2</em> induces the up-regulation of lncRNA <em>TUG1</em> to promote progression and adriamycin resistance in urothelial carcinoma of the bladder</p>

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Table 1 Clinicopathological features of patients with urothelialcarcinoma of the bladder (UCB)
Figure 2 Up-regulation of Nrf2 and TUG1 in ADM-resistant cells. (A and B) Nrf2 expression was measured in UCB cell lines (EJ-1, 5637, BIU-87 and T24) and normalhuman urothelial cells (SV-HUC-1) by RT-PCR and Western blot
Figure 3 Nrf2and *** positively regulates the expression of TUG1 in UCB cells. (A) BIU-87 andT24 cells were transfected with pcDNA-Nrf2, si-Nrf2 or matched controls, and thetransfection efficiency was identified by Western blot
Figure 4 Knockdown of eitherviability was analyzed at the indicated time-points (0, 1, 2, 3 days after transfection) by CCK-8 assay
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