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Should we titrate ventilation based on driving pressure? Maybe not in the way we would expect

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Figure

Figure 1 Effects of loss of aeration on the driving pressure. The use of 500 mL tidal volume applied to a lung with no loss of aeration and high compliance does not result in tidal hyperinflation (A)
Figure 2 Effects on driving pressure and stress index of the application of the same tidal volume on lungs with different characteristics
Table 1 Driving pressure and mortality in 7 randomised trials in ARDS patients

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