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Fibronectin rich fibrillar extracellular matrix controls cell migration during amphibian gastrulation

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Figure

Fig. 1. Scanningelectronmicrographs.Gastrulationof Pleurodeleswaltl embryosfrom rhe vegetal aspect.!A) Blastopore15a pigmentedarea justbeginningto Invagmate(81 BlastoporenearlV a complereCircleICIYolk plug disappearsfrom surfaceand blastoporecloses.Bar: 500,um.
Fig. 3. Fluorescent
Fig. 5. Scanningelectronmicrographof the in vivo effectof Fab' fragmentsof anti-FNduringgastrulation.PleurodeleswaltlembryosweremJcrolnjectedat theearly gastrulastage(StageBb) andobserved24 h later
Fig. 6. Migratorybehaviorof mesodermalcells in lIitrofromPleurodeleswalt/gastrulaeon a substrateconditionedby FN and TN
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