• No results found

Steroidogenic Enzymes and Stem Cell Markers Are Upregulated during Androgen Deprivation in Prostate Cancer

N/A
N/A
Protected

Academic year: 2020

Share "Steroidogenic Enzymes and Stem Cell Markers Are Upregulated during Androgen Deprivation in Prostate Cancer"

Copied!
8
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Table 1. Patient characteristics.
Figure 1. Schematic overview of the steroidogenic pathway. AMACR, α-methylacyl-CoA racemase; FASN, fatty acid synthase; SREB, Gprotein-coupled receptor; StAR, steroidogenic acute regulatory protein; CYP, cytochrome P450; CYB5, cytochrome b5; HSD, hydroxys-teroid dehydrogenase; AKR, aldo-keto reductase; SRD, 5α-reductase; UGT, UDP glucuronosyltransferase; green boxes, adrenal androgens;blue box, testicular androgen; yellow box, tissue androgen.
Table 2. Mean fold-change values in mRNA expression of steroid metabolism/signalingrelated genes in clinical samples of LG, HG, met and CRPC.
Figure 3. Relative expression values of enzymes involved in steroid metabolism and ARCYP11A1, CYP17A1, HSD3B2 and HSD17B3, for which the Cp-values were high (Cp > 36),thase; HSD, hydroxysteroid dehydrogenase; AKR, aldo-keto reductase; RDH, retinol dehy-dro
+3

References

Related documents

DICTIONARIES WITH POLISH ANATOMICAL TERMINOLOGY Józef Mayer (anthropologist) and Fryderyk Sko- bel (physiologist), both professors at the Jagiello- nian University in 1838 published

The functioning of Bonding based forwarding technique has been defined to take advantage of Community-Independent routing, to gain a high delivery probability in association

In doing so, it illuminates the journey towards and the realities of a group whose views are currently unrepresented in research on school leadership or that of the experiences of

," was enacted prior to the homestead law and that, since the homestead act did not expressly provide for an exemption from a judgment lien, the homestead

• The construct shifted from a state of conflict in September 2017, by January 2018 it had almost passed out of a state of conflict and by March 2018 it was on the verge

• Direct funding to purchase fuel-efficient vehicles for the federal fleet: The Recovery Act appropriated $300 million to GSA for capital expenses associated with acquiring

Before the Virginia State Corporation Commission and the North Carolina Utilities Commission. Filed on July

the microscopic solution of v 2 − f model. Then, employing the volume average technique, the macroscopic transport equations of continuity, momentum and k- ε model are derived