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 SYNTHESIS, PHARMACOLOGICAL EVALUATION AND LIGAND-PROTEIN INTERACTION STUDY OF HYBRID UREA AND THIOUREA DERIVATIVES AS ANTIHYPERGLYCEMIC AGENTS

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Figure

Table 2: Level of Total cholesterol, Triglycerides, HDL, LDL, and VLDL in diabetic control and experimental groups of rats after 14 days experimental period
Figure 2: Level of fasting blood glucose levels (A) and body weight (B) in diabetic control and experimental groups of rats after 14 days of treatment
Figure 4: The levels of plasma protein (A), blood urea (B) and serum creatinine (C) in diabetic control and experimental groups of rats after 14 days experimental period
Figure 6: Molecular docking analysis of the ligand binding pocket of αacids (a-His 111, Lys 155, Phe 157, Phe 177, His 239, Asn 241, His 279; b- Tyr 71, Asp 68, Val 108, Asp 214, His 348, Asp 349; c- Tyr 313, Asp -glucosidase MAL12 model structure obtained

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