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Sleep deprivation of rats increases postsurgical expression and activity of L-type calcium channel in the dorsal root ganglion and slows recovery from postsurgical pain

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Figure

Fig. 1 Perioperative SD prolongs postsurgical pain.rats in the sham, sham+SD, incision, and incision+SD groups (5 to 10 rats per group)
Fig. 2 Perioperative SD increases expression of L-type HVA channels in lumbar (L4R-type, P/Q-type, and N-type channel proteins in the L4results in A (10 rats per group)
Fig. 3 Perioperative SD increases expression of L-type HVA channels in lumbar (L4Tukey test: F(3, 8) = 74.13, **–6) DRG neurons, mainly in medium/large cells
Fig. 4 Perioperative SD increases the activity of HVA calcium channels and L-type calcium channels and excitability in large DRG neurons at 9days after surgery
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