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Wnt5a and Wnt11 regulate mammalian anterior posterior axis elongation

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Figure

Fig. 2. Defective CE and PCP signaling inthe notochord of Wnt5a−/−; Wnt11−/−embryos. (A,B) Whole-mount in situhybridization for brachyury (T ) in ventral viewsof the notochord at E8.5
Fig. 3. Wnt5a(D-L) Expression ofindicates extension of unsegmented mesoderm. (M-R) Expression ofthe posterior of embryos at E8.5 in dorsal view (M-O) and in tail buds of E9.5−/−; Wnt11−/− embryos display malformed heart and tail bud.(A-C) Heart formation i
Fig. 4. Reduced and irregular somite formation in Wnt5aDll1Wnt11indicated probes in E9.5 embryos
Fig. 5. Ectopic cell accumulation in Wnt5a(D,Dexpression of the indicated genes in E8.5 embryos
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