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Excitatory neurons sculpt GABAergic neuronal connectivity in the C elegans motor circuit

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Figure

Fig. 1. Cholinergic neuromuscular transmission is impaired in unc-3(e151)(middle and bottom) animals expressing GFP-tagged AChRs in body wall muscles ((gray) synapse onto inhibitory GABAergic motor neurons (blue) and onto body wall muscles (brown)
Fig. 2. unc-3 mutation causes
Fig. 3. Gross morphologicaldevelopment of GABA motorneurons and muscles does notrequire cholinergic innervation.(A-C′) Confocal images of the ventralnerve cord and body wall musclesposterior to the vulva of an adultwild-type (A,A′), unc-3(e151) mutant(B,B′
Fig. 4. Impaired cholinergic innervation alters the distribution and size of GABA synapses
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