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miR-135b-5p inhibits LPS-induced TNF aproduction via silencing AMPK phosphatase Ppm1e

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Academic year: 2020

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Figure

Figure 1: Expression of miR-135b-5p downregulates Ppm1e in human macrophages. A. miR-135b-5p complements Ppm1e’s 3’ untranslated regions (UTRs, position 517-524) (A)
Figure 2: miR-135b-5p activates AMPK signaling and inhibits LPS-induced TNFα production in human macrophages
Figure 4: AMPK activation is required for miR-135b-5p’s inhibition on LPS-induced TNFα production
Figure 5: miR-135b-5p inhibits LPS-induced ROS production, NFκB activation and TNFα mRNA expression

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