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HPV16 E6-E7 induces cancer stem-like cells phenotypes in esophageal squamous cell carcinoma through the activation of PI3K/Akt signaling pathway in vitro and in vivo

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Academic year: 2020

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Figure

Figure 1: HPV16 E6-E7 lentiviral vector stably transfected ESCC cells. A. Western blotting detected the HPV16 E6-E7 protein expression in ESCC cells (Eca109-control, Eca109-psb, TE-1-control and TE-1-psb cells)
Figure 2: HPV16 E6-E7 promotes spherogenesis ability and reduces G0/G1 cell cycle arrest in ESCC cells
Figure 3: HPV16 E6-E7 increases chemoresistance, radioresistance and anti-apoptosis ability after ionizing radiation in ESCC cells
Figure 4: PI3K/Akt signaling pathway activation and increased p75NTR expression induced by HPV16 E6-E7 were inhibited by LY294002 in ESCC cells.western blotting
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