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Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

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Academic year: 2020

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Figure

Figure 1: Higher number of mutations in primary samples is associated with a worse OS
Figure 3: Dynamics of subclones marked by PIM1 and BCL2 mutations during disease progression
Figure 4).TP53observed a loss of initially detected CREBBP mutations  mutations were shown to be present at in the samples of r/r disease in three of five patients
Figure 5: Three different relapse patterns in DLBCL. Analyzing patterns of primary and relapsed diseases we observed distinct patterns of relapse

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