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Blood flow reprograms lymphatic vessels to blood vessels

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Figure

Figure 1Late separation of the blood and lymphatic circulations in SLP76-deficient mice
Figure 2Mesenteric SVs in adult endothelial molecular markers LYVE1 and PROX1, but not the blood endothelial marker vWF
Figure 3Mesenteric SVs in adult flow through the intestinal and mesenteric vessels of neonatal wild-type, neonatal SLP76-deficient radiation chimeras (KO chimera) develop a vascular phenotype like that observed in KO neonates
Figure 4Genetic lineage tracing demonstrates that the blood endothelial cells lining mesenteric SVs in exposed to tamoxifen as neonates reveals YFP only in PROX1Slp76cells of the SVs shown are YFPStudies were performed as described in that line large SVs (
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