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Activation of hypothalamic S6 kinase mediates diet induced hepatic insulin resistance in rats

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Figure

Figure 1HFD feeding for 1 d blunts insulin signaling in the MBH at the level of IRS-1 without altering hepatic insulin signaling
Figure 2HFD feeding for 1 d induces insulin resis-
Figure 5Hypothalamic overexpression of CA-S6K leads to insulin resistance in the basal pancreatic clamp
Figure 7Hypothalamic overexpression of CA-S6K leads to insulin resistance under hyperinsulinemic-euglycemic clamp conditions
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