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Endothelial to mesenchymal transition drives atherosclerosis progression

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Figure

Figure 1. Shear stress downregulates FGFR1 expression and upregulates TGF-β(***ing. The bar graph of qRT-PCR results is representative of 4 independent experiments (*Keuls post-hoc test for multiple comparison correction)
Figure 2. Shear stress downregulates FGFR1 expression and upregulates TGF-β signaling in vivo
Figure 3. FGF signaling activity and EndMT extent in a mouse atherosclerosis model. (Quantification of the number of luminal ECs expressing FGFR1, p-ERK, and NOTCH3 (***t(fluorescence staining of NOTCH3 in aorta and plaque sections in A) Immunofluorescence
Figure 4. Effect of endothelial FGF signaling suppression on atherosclerosis in mice after 4 weeks of HFD
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