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SGK1 Inhibits ULK2 Autophagy Activity

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Academic year: 2020

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Figure

Figure 1. HE293 cell autophagy activity in response to insulin or GSK650394 treatment
Figure 2. The phosphorylation on (Ser507 and/or 750) of ULK2 by SGK1. (a) The mouse ULK2 (1036aa length) topology
Figure 3. The interaction of ULK2 mutant with AMPK1 depending on Ser507 and 750 phosphorylation
Table 1. Comparison of ULK2 cell viability with its WT, S750A or S750D mutant. EGFP ULK2WT or its S507AS750A or S507DS750D mutant or EGFP vector was transfected and the rate of apoptosis was measured by FACS

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