• No results found

Michaelis-Menten from an In Vivo Perspective: Open Versus Closed Systems

N/A
N/A
Protected

Academic year: 2020

Share "Michaelis-Menten from an In Vivo Perspective: Open Versus Closed Systems"

Copied!
13
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Fig. 2. Schematic description of the Michaelis-Menten model in an in vitro (closed) environment (Left) and in an in vivo (open) environment (Right), in which three processes have been added: Input of drug (Input), enzyme synthesis rate (k syn ) and enzyme
Fig. 3. Semi-logarithmic plot of observed ( filled symbols) and model- model-predicted (Eq
Table II. Parameter estimates for the data from PK22
Fig. 5. Acute doses in the open system: Log-linear and linear graphs of S (t) (top left and top right) and linear graphs of E (t) (bottom left) and ES (t) (bottom middle); total enzyme concentration E tot (t) (bottom right) for seven initial substrate conc
+5

References

Related documents

Although Congress' goal is to prevent future terrorist attacks, immigration restrictions suggested in the Terrorist Interdiction Act of 1993 and the Exclusion and

Be sure the product insert is current for the test system in use, the correct specimen type is used, the proper reagents (testing solutions) are added in the correct order, and

These early results opens up two major directions of re- search: (1) as to identify the taxonomy features of unknown snakes using feature auto- matic feature analysis and (2) to

Figure A.4 Male and female lists after four rounds of the Gale-Shapley algorithm 55 Figure A.5 (Irving, Leather, and Gusfield 1987) Male and female male- optimal

an idiopathic angioedema has been described in patients with normal C1-INH functional levels, no family history, and no response to high-dose antihistamines;

We combined the asthma control data set with patient attributes and environmental variables to develop machine learning models to predict a child ’ s asthma control deterioration

Interestingly, the control group of women had similar nutrient intake patterns of lower energy (38%), lower carbohydrate (57% ~ 63%) and higher levels of protein (14%) than

The attack is based on two observations: Since session key collisions for the same message are easy to detect, it is possible to recover one session key with a simple