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Effect of COX-2 inhibition on tendon-to-bone healing and PGE2 concentration after anterior cruciate ligament reconstruction

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Figure

Fig. 1 The bone tunnel was subdivided as a tunnel aperture (A) and mid‑tunnel (M) sections
Fig. 2 At the time point of examination, the tendon graft condition was classified morphologically as follows: a grade I—good condition (no atrophy, clearly demarcated from the rest of the joint structures); b grade II—atrophic (decrease of the transplant diameter); c grade IIIa—distinctly atrophic (clear decrease of the transplant diameter, transparent); d grade IIIb—distinctly atrophic and in part highly covered fibrinously, difficult to delimit from the surrounding soft tissues)
Fig. 3 The bone density and the bone area were examined in a defined measurement area around the bone tunnel in the pQCT
Fig. 5 The synovial PGE2 concentration was significantly reduced after 3 weeks application of COX‑2 inhibitor and was significantly increased 3 weeks after the last administration of COX‑2 inhibitor in comparison to the 3‑week examination time point
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