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Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies

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Figure

Figure 1. Hydroxyeicosatetraenoic acid–phospholipids (HETE-PLs) restore thrombin generation in FVIII-deficient plasma
Figure 2. HETE-PLs enhance thrombin generation in the absence of FIX or FXI, or in the absence of tissue factor pathway inhibitor (TFPI) and FVIII combined
Figure 3. HETE-PL restoration of hemostasis in mice lacking FVIII and enhancement of thrombin generation in FVIII deficiency, with/without tissue factor pathway inhibitor (TFPI) inhibition
Figure 5. HETE-PLs containing membranes directly bind Gla domain proteins, and specific HETE-PL positional isomers optimally support coag-ulation
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