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Biocompatible nanocomposite for PET/MRI hybrid imaging

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Figure 1 Schematic representation of the synthesis of Magh-1-PNPs-NODA.Abbreviations: CAN, ceric ammonium nitrate; PNPs, polyethyleneglycol-based nanoparticles; NODA, 2,2′-(7-(4-((2-aminoethyl)amino)-1-carboxy-4-oxobutyl)-1,4,7-triazonane-1,4-diyl)diacetic acid; PLGA-b-PEG, poly(D,L-lactide-co-glycolide)-block-poly(ethylene glycol).
Table 1 Relaxivity values obtained for Magh, Magh-1-PNPs, and Magh-1-PNPs-NODA
Figure 2 TEM image and relative DLS measurements of Magh-1-PNPs. TEM image (A) and relative DLS measurements (B) of Magh-1-PNPs.Abbreviations: TEM, transmission electron microscopy; PNPs, polyethyleneglycol-based nanoparticles; DLS, dynamic light scattering.
Figure 4 TLC profiles obtained for 68Ga-labelled NPs (red line, Rf = 0) and free EDTA-68Ga complex (black line, Rf = 0.35)
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