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Design and application of chitosan microspheres as oral and nasal vaccine carriers: an updated review

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Figure

Figure 1 Structure of chitin and chitosan.
Figure 2 Scanning electron microscope photographs of CMs, BBD-loaded CMs, MCMs, and BBD-loaded MCMs (5000×).Notes: Bar represents 5 µm
Figure 3 Representative structure of thiolated chitosan: (A) general structure of thiolated chitosan modified by an –SH group (X: linker) and (B) chitosan-N-acetyl-cysteine (modification of chitosan at the D-glucosamine unit by N-acetyl-cysteine).
Figure 4 Schematic representation of functional interaction between TCMs and mucin in mucosal vaccine delivery

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