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The mechanistic and evolutionary aspects of the 2′- and 3′-OH paradigm in biosynthetic machinery

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Figure

Figure 2 The second step of the aminoacylation reaction catalyzed by AspRS. The terminal 3′-OH ribose is positioned for attack on theaspartyl-adenylate carboxyl group
Figure 3 Superposition of crystal structures for two class I and class II aaRSs complexed with tRNAs, on that of EF-Tu and tRNA.(a) Overlay of class I CysRS and EF-Tu with their tRNAs (CysRS in green, PDB Code-1V0B; EF-Tu in red, PDB Code 1B23; tRNAs in or
Figure 4 Superposition of the catalytic cores of class II SepRS and PheRS (PheRS colored in red, blue, and green

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