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Meta-analysis of the association of the haptoglobin genotype with cardiovascular outcomes and the pharmacogenomic interactions with vitamin E supplementation

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Figure

Figure 1 Search strategy for studies used in our meta-analysis.
Figure 2 Hp 2-2 genotype and risk of CV events and effect of vitamin E on major CV outcomes.Notes: (A) Random effect meta-analysis of cohort studies and RCTs for CV events between Hp 2-2 and non-Hp 2-2 genotypes
Figure 4 Hp 2-2 genotype and risk of all-cause mortality.Note: Random effect meta-analysis of cohort studies and RCTs for all-cause mortality between Hp 2-2 and non-Hp 2-2 genotypes.Abbreviations: DHS, Diabetes Heart Study; Hp, haptoglobin; RCT, randomized controlled trial; WHS, Women’s Health Study.
Figure 7 Hp 2-2 genotype and risk of ESRD.Note: Random effect meta-analysis for ESRD between Hp 2-2 and non-Hp 2-2 genotypes.Abbreviations: DCCT, Diabetes Control and Complications Trial; EDC, Epidemiology of Diabetes Complications; ESRD, end-stage renal disease; Hp, haptoglobin; RCT, randomized controlled trial.
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