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The role of the pathology department in the preanalytical phase of molecular analyses

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Figure 1 Overview of the general responsibilities of surgical, pathology, and molecular medicine departments in the tissue analysis flow.Note: The pathology departments are at the core of tissue analysis, thus ensuring the quality control for tissue processing in all of the departments involved in biomedical research and in state-of-the-art molecular analyses.Abbreviations: CGH, chorionic gonadotrophin; FFPE, formalin-fixed paraffin-embedded; MALDI TOF, mass spectrometry; PCR, polymerase chain reaction; qPCR, quantitative PCR.
Figure 2 The steps of the preanalytical phase and their matching with the times of warm/cold ischemia.Note: Most steps are possible during cold ischemia, thus reducing as much as possible processing time and ensuring a good tissue quality for molecular testing.Abbreviation: FFPE, formalin-fixed paraffin-embedded.
Figure 3 Pathology diagnosis in hematological malignancies.Notes: (A) Bone marrow biopsy of a T-cell-rich/diffuse large B-cell lymphoma

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