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Characterizing heterogeneity in leukemic cells using single cell gene expression analysis

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Figure

Figure 1 t-Distributed stochastic neighbor embedding (t-SNE) analysis of FACS and qPCR single-cell gene expression data
Figure 2 Hierarchical clustering of the single-cell gene expression data. Each column corresponds to a specific gene and each rowcorresponds to a single cell
Figure 3 Mapping cellular hierarchy using SPADE analysis. (A) The cellular hierarchy in the normal hematopoietic system is represented bythe SPADE tree (adapted from [20]), on which the leukemic and normal cells are mapped as described in the main text
Figure 4 Experimental validation of the functional difference between the two leukemic cell subtypes
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