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Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins

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Figure

Figure 1 Isolation of Brd- and HP1-bound mononucleosomesSchematic of protocol used to isolate nucleosomes bound to FLAG-histone code readers (HCRs).bound nucleosome purifications
Figure 2 Histone H3 and H4 residue-specific PTMs quantified by mass spectrometry(c)Additional file 2
Figure 3 Quantification of PTMs on histone H3 and H4 peptides isolated with HP1 and Brd proteinsHeatmap depicting all modified forms of H4 peptides on HP1- and Brd-bound nucleosomes by mass spectrometry
Figure 4 Mapping of Brd- and HP1-bound nucleosomes to their genomic locations. (a) Chromosome maps showing the density of Brd-and HP1-bound nucleosomes generated by Solexa Deep sequencing on chromosomes 17, × and 12
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