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Enhanced antagonism of BST 2 by a neurovirulent SIV envelope

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Figure

Figure 1. Viral replication in PBMC and MDM. (A) Schematic diagram of SIVsmE543-3, SIVsm804E, and 3 chimeric clones
Figure 2. Determination of the region(s) responsible for enhanced replication in MDM. (A) A schematic diagram of the chimeric viruses is shown
Figure 3. Determination of specific amino acid substitution(s) responsible for enhanced replica-tion in MDM
Figure 4. Influence of mutations on in vitro replication capacity. (A) Replication kinetics of SIVsmE543CT#1, 543CT#2, 543CT#3, 543CT#4, and 543CT#154 on PBMCs and MDMs
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