• No results found

CDK4 is an essential insulin effector in adipocytes

N/A
N/A
Protected

Academic year: 2020

Share "CDK4 is an essential insulin effector in adipocytes"

Copied!
15
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Figure 1. Positive correlation between CDK4 activity and WAT mass. (weight, Cdk4A) Expression levels of CCND1, CCND2, CCND3, CDK4, and CDK6 proteins in mouse eWAT, BAT, brain, muscle, heart, kidney, lung, spleen, and liver
Figure 2. Positive correlation between CCND3 expression and human VAT mass.son’s  (A–D) Correlation between the CCND3/ACTB ratio (n = 32, Pearson’s r = 0.3717, P < 0.05) (A), the CCND1/ACTB ratio (n = 32, Pear-r = –0.04574, P < 0.05) (B), the CCND2/ACTB ra
Figure 3. CDK4 promotes insulin sensitivity in vivo. (Cdk4Cdk4A–C) Fasting glycemia in Cdk4+/+ and Cdk4nc (n = 8) mice (A), Cdk4flox/flox infected with AAV8-mini/aP2-null or AAV8-mini/aP2-cre vectors (n = 5–4) (B), and Cdk4+/+ and Cdk4R24C/R24C (n = 12) mi
Figure 4. CDK4 represses lipolysis and is a positive modulator of lipogenesis. ((and experiments in eWAT explants from A) Quantification of TG content of eWAT from Cdk4+/+ and Cdk4nc mice n = 3)
+5

References

Related documents

25 Moscow State University, Moscow, Russia 26 Institute for High Energy Physics, Protvino, Russia.. 27 Lancaster University, Lancaster, United Kingdom 28 Imperial College,

The frequency and nature of the mutations in UNC93A in ovarian tumours and cell lines suggests the following. Firstly, UNC93A is an unusual gene which is highly poly- morphic and

The outline is the polarization plot and the dotted lines represent the anodic reaction of (13) and the cathodic reaction of (14) that depict the corrosion behavior

While milk productivity and the delivery by large scale commercial dairy farmers is usually constant all year round, the quantity of milk produced within the

The Supreme Court's decision in Diehr brings our review of the law concerning hybrid inventions essentially up to date. At present, the cate- gorization of hybrid inventions

Limitations of HPI confirmed that environmetrics like principal component analysis and cluster analysis, in combination with metal concentration analysis

Firstly, it gives a profound comprehension of the influence of CSR on customers’ behaviour, because it explores the effects of varied aspects of CSR on