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p22phox confers resistance to cisplatin, by blocking its entry into the nucleus

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Figure

Figure 1: Expression of p22phox was significantly higher in CDDP-resistant than CDDP-sensitive OSCC tissues
Table 1: Clinicopathological information of the CDDP-sensitive and CDDP-resistant OSCC patients
Figure 2: Down-regulation of p22phox increased sensitivity to CDDP-induced cytotoxicity
Figure 3: Increased survival rates of p22phox stable lines treated with CDDP. Oral cancer cells stably expressing p22phox (p22phox line #1 and #2) were treated with increasing concentrations (1, 5, 10, 20 and 30 μM) of CDDP for 48 h
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