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Dominant negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency

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Figure

Figure 1. Pedigree analysis in patients with IKZF1individuals are shown in black. Diagonal lines indicate deceased individuals
Table 2. Immunological features of PBMCs from patients with IKZF1N159S/T mutationsA
Figure 2. Peripheral T cell phenotypes associated with heterozygous IKZF1with a paired healthy control donor (Ctrl1, Ctrl2, and Ctrl3)
Figure 3. Functional T cell defects associated with heterozygous IKZF1N159S/T mutations
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