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Targeted Mesoporous Iron Oxide Nanoparticles-Encapsulated Perfluorohexane and a Hydrophobic Drug for Deep Tumor Penetration and Therapy

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Figure

Figure 1. (a) Schematic illustration of the lactoferrin-capped mesoporous iron oxide nanoparticle (Lf-MION)
Figure 2. SEM images of Lf-MIONs prepared using various concentrations of lactoferrin for coating with different magnifications: (a, b) 0 %, (c, d) 1 %, and (e, f) 2 %
Figure 3. (a) Confocal laser various Cumulative PTX release from Lf-MIONs after 5 min of a high-frequency magnetic field lating perfluorohexane (PFH) before and after heating at 75 °C for 1 second
Figure 4. (a-f) Cellular uptake of quantum dot (QD)-loaded (a-c) Lf-MIONs and (d-f) MIONs in RG2 cells after 30 min, 1 h, and 2 h of incubation: the QD red fluorescence increases over time from many cell regions, including the cytoplasm
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