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Peripheral nervous system insulin resistance in ob/ob mice

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Figure

Figure 1 Ob/obshowed reduced insulin sensitivity inthis dose lowered the blood glucose of nondiabetic controls by approximately 3.6 mmol/L.elevated blood glucose and serum insulin levels
Figure 2 Ob/ob mice develop mechanical allodynia. Mechanicalthresholds were tested using von Frey monofilaments at 8, 9, 10,and 11 weeks of age
Figure 3 Intrathecal insulin-induced Akt activation is blunted in the PNS of ob/ob mice
Figure 5 The PNS of ob/ob mice displayed reduced Akt activation in response to intrathecal IGF-1
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