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Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies

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Figure

Figure 3ATD2B proteinsIfenprodil and RO25,6981 titration curves of soluble 6 × His-Ifenprodil and RO25,6981 titration curves of soluble 6 × His-ATD2B proteins
Table 1: Binding properties of ligands to soluble 6 × His-ATD2B protein and their inhibition on heterologously expressed NR1-1a/NR2B receptors in Xenopus oocytes.
Table 2: Comparison of KD values for the wild type and mutant 6 × His-ATD2B proteins.

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