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Suberoylanilide Hydroxamic Acid as a Potential Therapeutic Agent for Human Breast Cancer Treatment

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Figure

Fig. 1.SAHA inhibits clonogenic growth ofhuman breast cancer cells. (A) MCF7, (B) MDA-MB-231, and (C) MDA-MB-435 cells were treatedwith suberoylanilide hydroxamic acid (SAHA) at
Fig. 2.ment were floating dead cells that increased innumber as SAHA concentration increased
Fig. 3.breast cancer cells.
Fig. 4.Dose-dependent effect of SAHA on cellcycle progression in human breast cancer cells.MCF7, MDA-MB-231, and MDA-MB-435 cellswere treated with suberoylanilide hydroxamic acid(SAHA) at concentrations ranging from 0.1 to 10 �M for 24 hr or 48 hr, and then analyzed for cell
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