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Anti-fibrotic effects of tannic acid through regulation of a sustained TGF-beta receptor signaling

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Academic year: 2020

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Figure

Fig. 1 Inhibition of myofibroblast differentiation by tannic acid. a, b, Inhibition of Collagen-1 and SM-a-actin (SMA) expression by tannic acid (TA) in primary cultures of human lung fibroblasts in response to TGF- β (1 ng/ml, 48 h)
Fig. 3 Inhibition of bleomycin-induced pulmonary fibrosis by tannic acid. Tannic acid (TA) treatment (10 mg/kg, i.p., daily) started 7 days after intratracheal administration of bleomycin, and mice were sacrificed on day-21

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