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Mitoriboscins : mitochondrial based therapeutics targeting cancer stem cells (CSCs), bacteria and pathogenic yeast

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Figure

Figure 1: The endo-symbiotic theory of mitochondrial evolution: Implications for modern drug development
Figure 4: Chemical structures of the top 10 hits. The most promising top 10 hits of the phenotypic drug screen were organized into 4 groups based on chemical structure: Group 1: a) 23/E9 (BDI34121280); b) 23/G4 (BDH34061768); and c) 25/E3 (BDH34062170)
Figure 6: Effects of 3 top hit compounds on cell viability. A.fibroblasts. The SRB assay was performed after 72 hours of treatment
Figure 7: Effects of compound 23/G4 on the metabolic activity of MCF7 human breast cancer cells
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