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S(+) Flurbiprofen Shows Potent PGE2 Inhibitory Activity in Inflammatory Cells, Superior Cell Transport Activity and Skin Permeability

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Figure

Table 1. Inhibitory effect of SFP, FP and RFP on the production of prostaglandin E2 by rat peritoneal leukocytes
Figure 1. Binding property of the test drugs to PMNs or erythrocytes. After incubation of SFP (3 nM) or RFP (3 nM) with PMNs (3 × 107 cells/mL) and erythrocytes (1 × 109 cells/mL), the concentration of the drugs in the culture me-dium were measured by HPLC
Figure 3. Skin permeability profiles of SFP, RFP and FP in the YMP model. The Q values of SFP, RFP and FP were evaluated using YMP skin

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