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B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines

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Figure

Figure 1: Primary human peripheral blood APCs exhibit spontaneous uptake of plasmid DNA
Figure 2: Primary human B cells encode plasmid mRNA and mediate expansion of cognate antigen specific CD8 T cells upon plasmid DNA treatment
Figure 2a, mRNA for EGFP or OVA was detected only in B
Figure 4: Mouse B cells, and not dendritic cells, are able to expand antigen specific CD4 and CD8 T cells following DNA stimulation
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