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Novel agents that downregulate EGFR, HER2, and HER3 in parallel

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Figure

Figure 1: EGFR, HER2, and HER3 Disulfide Bonds as a Therapeutic Target. A. X-ray crystal structures of the extracellular domains of EGFR, HER2, and HER3 with cysteine residues shown in red
Figure 2: EGFR/HER2/HER3-targeted Compounds Induce Cell Death and Suppress Response to EGF
Figure 3: Forced EGFR Expression Sensitizes Cells to EGFR/HER2/HER3-targeted Compounds
Figure 4: Identification of the Pharmacophore in EGFR/HER2/HER3-targeted Compounds. A
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