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HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib

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Figure

Table 1: Bozepinib shows broad anti-proliferative effects and significantly improved the therapeutic index (TI).
Figure 1: Western blot and densitometric analysis of different proteins related with cancer cell proliferation after treatment with 5 µM of Bozepinib
Figure 2: Capillary network formation and cell migration assays. (A) Representative light microscopy analysis of cells at different culture stages and HUVEC grown on Matrigel™ coated wells with EGM-2 medium
Figure 3: Gene expression profiling of MDA-MB 468 Bozepinib-treated breast cancer cells
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