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Type I IFN innate immune response to adenovirus mediated IFN γ gene transfer contributes to the regression of cutaneous lymphomas

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Academic year: 2020

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Figure

Figure 1Functional annotation of genes upregulated after treatment with Ad-IFN-γ using the GO mining tool (NetAffx)
Figure 2Genes shared and unique-and/or Ad-null. Venn dia-gram represents genes that are shared by or spe-cific for data sets obtained from Ad-IFN-PBMCs (orange) and Ad-null infected PBMCs (blue)
Figure 3Ingenuity pathway analysis (IPA) of functional associations between IFN-γ– and IL-2–associated gene networks after Ad-null (A and C) and Ad-IFN-γ infection (B and D)
Figure 4Classification of the skin lesions using OR predictor genes. The heatmap was obtained by unsupervised hierarchical clustering of the baseline
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