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Neurog2 is a direct downstream target of the Ptf1a Rbpj transcription complex in dorsal spinal cord

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Academic year: 2020

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Figure

Fig. 1. A dorsal-neural-tube-specific enhancerfor gene and transgenic constructs (A) showing thelocation on mouse chromosome 3 of the 3enhancer (TgN2-4) that directs expression of a transverse section of the neural tube illustratesPtf1a is restricted to an
Fig. 2. Ptf1a, Neurog2 and TgN2-4 overlap in the dorsal neural tube. (magnification of the region boxed in A
Fig. 3. PTF1-J trimeric complex binds the Neurog2bind as a heterodimer with E12 (lane 11)
Fig. 5. The Neurog2 3� enhancer requires Ptf1a
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