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Midkine promotes hepatocellular carcinoma metastasis by elevating anoikis resistance of circulating tumor cells

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Academic year: 2020

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Figure

Figure 1: Tyrosine kinase receptor B (TrkB) is involved in midkine-mediated anoikis resistance of hepatocellular  carcinoma (HCC) cells
Figure 2: Midkine induces anoikis resistance, growth and invasion of hepatocellular carcinoma (HCC) cells through  anaplastic lymphomakinase (ALK) activation
Figure 3: PI3K/Akt/NF-kB/TrkB signaling activated by anaplastic lymphomakinase (ALK) is required for midkine- midkine-induced anoikis resistance
Figure 4: Midkine promotes circulating tumor cell (CTC) survival and tumor metastasis in mice
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