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A plasmid containing CpG ODN as vaccine adjuvant against grass carp reovirus in grass carp

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Figure 1: Effect of plasmids containing CpG ODNs on CIK cells. (A) CIK cells were treated with PBS (control) or different plasmids and determined the proliferation activity by cell counting at 48 h post-stimulation
Figure 2: Antiviral activities of plasmids containing CpG ODNs in CIK cells. (A) CIK cells were stimulated with PBS (control) or plasmids containing CpG ODNs and subsequently challenged with GCRV at 48 h post plasmids administration
Figure 3: Immune responses to plasmids containing CpG ODNs in CIK cells. The mRNA expressions of CiTLR9 (A), CiRIG-I (B), CiIL-2 (C), CiIFNγ2 (D), CiNFκB1 (E) and CiNFκB2 (F) were measured at 0, 24 and 48 h post-infection
Figure 4: Immune responses of CiIFN1/3 to plasmids containing CpG ODNs. Left, the mRNA expressions of CiIFN1 (A) and CiIFN3 (B) were measured at 24 and 48 h post-infection
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